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Francis Ali-Osman Selected Research

1,1',3,3,3',3'- hexamethylindotricarbocyanine

1/2018Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts.

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Francis Ali-Osman Research Topics

Disease

30Neoplasms (Cancer)
01/2018 - 01/2002
19Glioma (Gliomas)
01/2019 - 07/2003
11Glioblastoma (Glioblastoma Multiforme)
06/2015 - 01/2002
9Brain Neoplasms (Brain Tumor)
01/2018 - 01/2002
7Melanoma (Melanoma, Malignant)
10/2014 - 04/2004
4Breast Neoplasms (Breast Cancer)
09/2016 - 09/2002
4Hypersensitivity (Allergy)
02/2016 - 04/2009
2Rib Fractures (Rib Fracture)
01/2021 - 01/2018
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 12/2010
2Wounds and Injuries (Trauma)
12/2019 - 01/2018
2Carcinogenesis
03/2011 - 08/2007
2Medulloblastoma
10/2008 - 07/2002
1Mucormycosis
12/2019
1Invasive Fungal Infections
12/2019
1Pneumonia (Pneumonitis)
01/2018
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
09/2016
1Asthma (Bronchial Asthma)
02/2016
1Eczema
02/2016
1Pain (Aches)
12/2015
1Hip Fractures (Intertrochanteric Fractures)
12/2015
1Delirium
12/2015
1Respiratory Insufficiency (Respiratory Failure)
12/2015
1Genomic Instability
01/2013
1Hepatocellular Carcinoma (Hepatoma)
07/2010
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
07/2010
1Residual Neoplasm
04/2010
1Disease Progression
06/2009

Drug/Important Bio-Agent (IBA)

14Proteins (Proteins, Gene)FDA Link
09/2016 - 01/2002
9Glutathione Transferase (Glutathione S-Transferase)IBA
12/2015 - 04/2003
7DNA (Deoxyribonucleic Acid)IBA
09/2016 - 01/2002
7Temozolomide (Temodar)FDA LinkGeneric
11/2010 - 09/2005
6Pharmaceutical PreparationsIBA
01/2018 - 12/2004
5ErbB Receptors (EGF Receptor)IBA
12/2015 - 10/2008
4Alkylating AgentsIBA
09/2016 - 07/2002
4Phosphotransferases (Kinase)IBA
12/2015 - 12/2004
4epidermal growth factor receptor VIIIIBA
03/2011 - 10/2008
4Glutathione (Reduced Glutathione)IBA
11/2010 - 05/2007
3MethyltransferasesIBA
09/2016 - 07/2003
3Biological ProductsIBA
02/2016 - 02/2011
3O(6)-Methylguanine-DNA MethyltransferaseIBA
03/2014 - 10/2006
3Cisplatin (Platino)FDA LinkGeneric
11/2010 - 10/2008
2Disulfiram (Antabuse)FDA Link
01/2018 - 03/2014
2O(6)-benzylguanineIBA
09/2016 - 07/2002
2ORALIT (ORS)IBA
02/2016 - 04/2009
2Tyrosine (L-Tyrosine)FDA Link
12/2015 - 06/2009
2A-Form DNA (A-DNA)IBA
03/2014 - 09/2005
2UbiquitinIBA
03/2014 - 01/2013
2Gefitinib (Iressa)FDA Link
08/2010 - 10/2008
2INO 1001IBA
08/2010 - 09/2005
2Melphalan (Alkeran)FDA LinkGeneric
07/2010 - 05/2007
2TransferasesIBA
07/2010 - 08/2007
2O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA
07/2010 - 08/2007
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
09/2009 - 12/2004
2Carmustine (FIVB)FDA Link
10/2008 - 07/2002
2Thromboplastin (Tissue Factor)IBA
07/2008 - 07/2003
2Alkyl and Aryl TransferasesIBA
10/2006 - 07/2002
2Messenger RNA (mRNA)IBA
04/2004 - 07/2003
2EnzymesIBA
02/2004 - 09/2002
1Imatinib Mesylate (Gleevec)FDA Link
01/2021
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2019
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2019
1Coloring Agents (Dyes)IBA
01/2018
11,1',3,3,3',3'- hexamethylindotricarbocyanineIBA
01/2018
1MutagensIBA
01/2018
1Estrogen ReceptorsIBA
09/2016
1O-(6)-methylguanineIBA
09/2016
1Fulvestrant (Faslodex)FDA Link
09/2016
1Narcotics (Narcotic Analgesics)IBA
12/2015
1Shelterin ComplexIBA
01/2015
1Mitogen-Activated Protein KinasesIBA
10/2014
1VemurafenibIBA
10/2014
1Proteasome Endopeptidase Complex (Proteasome)IBA
03/2014
1CopperIBA
03/2014
1StaurosporineIBA
03/2011
1AnisomycinIBA
03/2011
1Histamine Antagonists (Antihistamines)IBA
02/2011
1Biomarkers (Surrogate Marker)IBA
02/2011
1Mitoxantrone (Novantrone)FDA LinkGeneric
12/2010
1GemcitabineFDA Link
12/2010
1Serine (L-Serine)FDA Link
11/2010
1Poly(ADP-ribose) Polymerase InhibitorsIBA
08/2010
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
08/2010
1Sorafenib (BAY 43-9006)FDA Link
07/2010
1Proto-Oncogene Proteins B-rafIBA
07/2010
1Protein Isoforms (Isoforms)IBA
09/2009
1Transforming Growth Factor beta (TGF-beta)IBA
09/2009
1Epidermal Growth Factor (EGF)IBA
06/2009
1OligonucleotidesIBA
01/2009

Therapy/Procedure

16Therapeutics
01/2021 - 01/2002
9Drug Therapy (Chemotherapy)
03/2014 - 02/2004
2Artificial Respiration (Mechanical Ventilation)
01/2021 - 01/2018
2Length of Stay
01/2018 - 12/2015
1Debridement
12/2019
1Laparotomy
12/2019
1Blood Transfusion (Blood Transfusions)
12/2019
1Thoracotomy
01/2018
1Tracheostomy
01/2018
1Immunotherapy
02/2016
1Pain Management
12/2015
1Radiotherapy
01/2013